Common questions

Erectile dysfunction

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What is erectile dysfunction (ED)?

ED is a medical condition that causes problems getting or maintaining an erection.

Approximately 18 million men in the United States alone have ED ED is more common in older men, but can happen at almost any age—even to those who have never had issues with sexual activity before ED is treatable in most cases Talk to your doctor if you are experiencing any kind of ED

Learn more about ED.

What factors increase the risk for ED?

High blood pressure (hypertension) Diabetes (high blood sugar) High cholesterol Nerve diseases (such as Parkinson's diseaseA disorder that kills or damages nerve cells in a part of the brain that controls how muscles move. Symptoms may include shaking, stiffness, slow movement, and poor balance and coordination. or multiple sclerosis) Surgery or injury (especially prostateA gland in a man’s body located near the base of his penis. The prostate secretes a fluid that makes up the main portion of the fluid (semen) that a man ejaculates during an orgasm., bladder, or rectal surgery) Abnormal hormone levels (testosterone or thyroid) Lifestyle factors (like smoking, drinking alcohol in excess, being overweight, not being physically active, or using recreational drugs) Side effect of some medications (including high blood pressure medication and antihistamines) Emotional or personal issues (such as ongoing stress or relationship problems, depression, or anxiety about sexual performance)

Learn more about ED.

Does age play a role in ED?

As men get older, sexual function is more likely to decrease and ED becomes more common.

Getting older by itself does not lead to ED ED can be treated no matter your age* ED is often caused by other health problems that your doctor should know about, like heart disease or diabetes—which are also more common with age

*CIALIS is only for men aged 18 or older.

Learn more about ED.

How does CIALIS treat ED?

You should not get an erection just by taking CIALIS. Sexual stimulationThe act of sexually arousing a person through touch and/or emotional excitement. is required for CIALIS to work When you get an erection, blood flows into your penis and is temporarily trapped there, creating pressure in the surrounding chambers that causes your penis to expand. When you have ED, this process is interrupted CIALIS increases blood flow to your penis and may improve the ability to get erections and maintain them until sexual intercourse is successfully completed CIALIS may also improve the overall satisfaction with the hardness of erections After sexual intercourse is completed, the erection should go away. But in the rare event of an erection lasting more than 4 hours, seek immediate medical help to avoid permanent damage

Please see full Patient Information and talk to your doctor to learn more.

For the treatment of ED, how do the 2 CIALIS options differ?

CIALIS offers 2 options to treat ED: CIALIS for daily use (2.5 mg, 5 mg) A low-dose tablet taken once a day so you can attempt sex anytime between doses* You may be able to have successful intercourse in as early as 4 to 5 days, or you may get results earlier Your doctor may adjust your dose, depending on how your body responds to the medicine For the treatment of ED, the recommended starting dose of CIALIS for daily use is
2.5 mg
Do not take CIALIS more than one time each day

CIALIS for use as needed (5 mg, 10 mg, 20 mg) A tablet that you take as needed One 20-mg tablet works in as little as 30 minutes in some men* One dose can work for up to 36 hours* The recommended starting dose for CIALIS for use as needed in most patients is
10 mg
Do not take CIALIS more than one time each day

*Individual results may vary. Not studied for multiple attempts per dose.

In clinical trials, CIALIS for use as needed started to work in 30 minutes for some men who took
20 mg of CIALIS.

When taken as needed, CIALIS was shown to improve, up to 36 hours after dosing, the ability of men with ED to have a single successful intercourse attempt.

When treating my ED, what can I expect with CIALIS?

CIALIS for daily use (2.5 mg, 5 mg) 1 week to help improve ED You may be able to have successful intercourse in as early as 4 to 5 days, or you may get results earlier If you are not satisfied, talk to your doctor, who may recommend an adjustment to your CIALIS dosage

Do not take CIALIS more than one time each day.


CIALIS for use as needed (5 mg, 10 mg, 20 mg)

One 20 mg tablet works in as little as 30 minutes in some men* One dose can work for up to 36 hours*

Do not take CIALIS more than one time each day.


*Individual results may vary. Not studied for multiple attempts per dose.

In clinical trials, CIALIS for use as needed started to work in 30 minutes for some men who took
20 mg of CIALIS.

When taken as needed, CIALIS was shown to improve, up to 36 hours after dosing, the ability of men with ED to have a single successful intercourse attempt.

Benign prostatic hyperplasia

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What is benign prostatic hyperplasia (BPH)?

BPH is a medical condition in which the prostate A gland in a man’s body located near the base of his penis. The prostate secretes a fluid that makes up the main portion of the fluid (semen) that a man ejaculates during an orgasm. becomes enlarged and can cause problems associated with urination.


Learn more about BPH.

What causes the urinary symptoms of BPH?

When everything is working normally, the bladder stores urine until it is full, then empties all of the urine at once. The urine leaves the body through a thin tube called the urethra, which is surrounded by the prostate A gland in a man’s body located near the base of his penis. The prostate secretes a fluid that makes up the main portion of the fluid (semen) that a man ejaculates during an orgasm. gland.


With BPH, the prostate gland enlarges and can eventually interfere with urination by partially blocking the urethra.


Learn more about BPH.

Does age play a role in BPH?

BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra. symptoms, like needing to go frequently or urgently, can increase with age and often occur along with ED.


Learn more about BPH.

How may CIALIS for daily use (5 mg) treat ED and the symptoms of BPH?

CIALIS belongs to a group of medicines called phosphodiesterase 5 (PDE5) A class of drugs used to treat ED. PDE5 is an abbreviated term for phosphodiesterase 5, an enzyme that prevents blood vessels from relaxing and filling up with blood. PDE5 inhibitors help improve the ability to get and keep an erection by blocking PDE5, causing smooth muscle and blood vessels in the penis to relax. inhibitorsA class of drugs used to treat ED. PDE5 is an abbreviated term for phosphodiesterase 5, an enzyme that prevents blood vessels from relaxing and filling up with blood. PDE5 inhibitors help improve the ability to get and keep an erection by blocking PDE5, causing smooth muscle and blood vessels in the penis to relax. PDE5 is an enzyme found in many tissues in the body, including the prostate A gland in a man’s body located near the base of his penis. The prostate secretes a fluid that makes up the main portion of the fluid (semen) that a man ejaculates during an orgasm. and bladder PDE5 helps prevent blood vessels from relaxing and filling up with blood Blood flow to the penis is necessary to get and keep an erection CIALIS blocks PDE5 and causes smooth muscle and blood vessels in the penis to relax This relaxation leads to increased blood flow, which is necessary for getting and maintaining an erection CIALIS blocks PDE5 in the prostate and bladder, but the mechanism of how CIALIS reduces BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra. symptoms is not completely understood Some form of sexual stimulation The act of sexually arousing a person through touch and/or emotional excitement. is needed for CIALIS to work for ED

Which CIALIS option is recommended for the treatment of both ED and the symptoms of BPH?

CIALIS for daily use (5 mg) is the only approved treatment for both ED and the symptoms of BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra..

When treating my symptoms of BPH, what can I expect with CIALIS for daily use (5 mg)?

1 month to help improve BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra. symptoms You may see symptom improvement in as early as 2 weeks after beginning treatment, although it could take about 4 weeks

Learn more about CIALIS for daily use (5 mg).

Important considerations

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Can I take both CIALIS for daily use and CIALIS for use as needed at the same time to treat my ED?

Do not take CIALIS for daily use (2.5 mg, 5 mg) and CIALIS for use as needed (5 mg,
10 mg, 20 mg) at the same time. If you are taking one of the CIALIS dosing options and would like to start taking the other, talk to your doctor before discontinuing use You should not take any other ED treatment while taking CIALIS. Do not take CIALIS more than one time each day

Can CIALIS for use as needed treat men with ED and the symptoms of BPH?

Only CIALIS for daily use (5 mg) is approved to treat both ED and symptoms of BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra.. Do not take CIALIS more than one time each day.

CIALIS for use as needed is not approved to treat the symptoms of BPH

What should I do if I miss a dose of CIALIS for daily use (2.5 mg, 5 mg)?

If you miss a dose, take it when you remember. However, do not take CIALIS more than one time each day.

Can I split CIALIS tablets in half?

Do not split CIALIS tablets in half.

CIALIS tablets are not scored down the middle, so you may not be able to break one exactly in half If a CIALIS tablet is not split exactly in half, you may not receive an adequate dose If you do not get the proper dose, you may not get the results you are hoping for If your doctor thinks CIALIS is right for you, he or she will prescribe the recommended dosing option

Your doctor may adjust your dose depending on how your body responds to the medicine. Do not take CIALIS more than one time each day.

What is the most important information I should know about CIALIS?

Do not take CIALIS if you:

Take medicines called “nitrates”A type of medicine commonly used to treat heart problems. These medicines relax and widen blood vessels. This allows more blood to flow to the heart, which makes the heart work less hard. Some recreational drugs called "poppers," like amyl nitrite and butyl nitrite, also contain nitrates. such as isosorbide dinitrate or isosorbide mononitrate, which are often prescribed for chest pain, as the combination may cause an unsafe drop in blood pressure Use recreational drugs called “poppers”A slang term for various chemical compounds, including amyl nitrite and butyl nitrite, that are used for recreational purposes. The chemical compound is inhaled to increase sexual desire. like amyl nitrite and butyl nitrite Are allergic to CIALIS or ADCIRCA® (tadalafil), or any of its ingredients. Call your healthcare provider or get help right away if you experience any symptoms of an allergic reaction, such as: Rash Hives Swelling of the lips, tongue, or throat Difficulty breathing or swallowing

After taking a single tablet, some of the active ingredient of CIALIS remains in your body for more than 2 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications.


Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.

Who should not take CIALIS?

Do not take CIALIS if you:

Take any medicines called “nitrates”A type of medicine commonly used to treat heart problems. These medicines relax and widen blood vessels. This allows more blood to flow to the heart, which makes the heart work less hard. Some recreational drugs called "poppers," like amyl nitrite and butyl nitrite, also contain nitrates. Use recreational drugs called “poppers”A slang term for various chemical compounds, including amyl nitrite and butyl nitrite, that are used for recreational purposes. The chemical compound is inhaled to increase sexual desire. like amyl nitrite and butyl nitrite Are allergic to CIALIS or ADCIRCA® (tadalafil), or any of its ingredients. Symptoms of an allergic reaction may include: Rash Hives Swelling of the lips, tongue, or throat Difficulty breathing or swallowing

Call your healthcare provider or get help right away if you have any of the symptoms of an allergic reaction listed above.

What should I tell my doctor or healthcare provider before taking CIALIS?

CIALIS is not right for everyone. Only your healthcare provider and you can decide if CIALIS is right for you. Ask your healthcare provider if your heart is healthy enough for you to have sexual activity. Do not take CIALIS if your healthcare provider has told you not to have sexual activity because of your health problems. Before taking CIALIS, tell your healthcare provider about all your medical problems, particularly if you have or ever had:

Heart problems such as chest pain (angina), heart failure, irregular heartbeats, or heart attack Uncontrolled high or low blood pressure Stroke Liver or kidney problems or require dialysis Retinitis pigmentosa, a rare genetic (runs in families) eye disease Severe vision loss, including a condition called NAION Stomach ulcers or a bleeding problem A deformed penis shape or Peyronie’s disease A condition in which a hard lump (plaque) forms on the penis. Sometimes the lump makes the penis less flexible, which can be painful. It can also cause the penis to bend or arc during an erection. An erection that lasted more than 4 hours Blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia

Can other medicines affect CIALIS?

Tell your healthcare provider about all the medicines you take, especially:

Medicines called “nitrates,”A type of medicine commonly used to treat heart problems. These medicines relax and widen blood vessels. This allows more blood to flow to the heart, which makes the heart work less hard. Some recreational drugs called "poppers," like amyl nitrite and butyl nitrite, also contain nitrates. which are often prescribed for chest pain Alpha-blockers Also called alpha-adrenergic antagonists. A kind of medicine that treats a variety of health conditions, including high blood pressure, an enlarged prostate, and some circulation problems. Alpha-blockers relax certain muscles and help small blood vessels stay open and relaxed. This improves blood flow and lowers blood pressure., often prescribed for prostate problems Blood pressure medications Medicines for human immunodeficiency virus (HIV) or some types of oral antifungal medications Some types of antibiotics such as clarithromycin, telithromycin, erythromycin (several brand names exist; please contact your healthcare provider to determine if you are taking this medicine) Other medicines or treatments for ED CIALIS is also marketed as ADCIRCA for the treatment of pulmonary arterial hypertension. Do not take both CIALIS and ADCIRCA. Do not take sildenafil citrate (Revatio® )* with CIALIS

*The brands listed are trademarks of their respective owners and are not trademarks of Eli Lilly and Company. The makers of these brands are not affiliated with and do not endorse Eli Lilly and Company or its products.

What are the possible side effects of CIALIS?

The most common side effects of CIALIS are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle aches usually get it 12 to 24 hours after taking CIALIS. Back pain and muscle aches usually go away within 2 days. Call your healthcare provider if you get any side effect that bothers you or one that does not go away.

Uncommon but serious side effects include: An erection that won’t go away: If you get an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury In rare instances, men taking prescription ED tablets, including CIALIS, reported a sudden decrease or loss of vision or hearing (sometimes with ringing in the ears and dizziness). It’s not possible to determine if these events are related directly to the ED tablets or to other factors. If you have a sudden decrease or loss of vision or hearing, stop taking any ED tablet, including CIALIS, and call a healthcare provider right away


These are not all of the possible side effects of CIALIS. For more information, ask your healthcare provider or pharmacist.

How much does CIALIS cost?

Please check local pharmacies for actual retail prices, which may vary. Both national and regional managed care coverage has expanded for CIALIS for daily use, so be sure to contact your health plan’s member services to find out if you’re covered for a full month’s prescription.

How do I talk about ED with my partner?

Talking with your partner about ED may not be easy, but it can be helpful—for both of you. Remember that ED is treatable for most men If you and your partner avoid the conversation, neither of you can know what the other is thinking and feeling


You should be open and honest, as well as sensitive, about your partner’s needs and questions.

Remember to stick to the facts and to talk about ED as the medical problem it isReassure your partner that your ED is not her fault, but likely a medical issue

How do I talk about BPH with my partner?

Talking with your partner about BPH may not be easy, but it can be helpful—for both of you.

Keep your partner in the loop about what you’re experiencing Explain that BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra. symptoms are likely caused by a medical issue Remember—BPH symptoms are treatable

My partner has ED. What should I know?

You may be thinking, “It’s me.” But you should know that ED is a real, treatable medical condition often caused by another health problem (like diabetes or heart disease) or by certain medicines.


Learn everything you can about ED and available treatment options, and share that information with your partner Once you both have all the facts, your partner can work with his doctor to make a better informed decision about what to do next Talk with your partner about what’s going on and encourage him to visit his doctor to see if he has ED Offer to make an appointment for him or go to the doctor with him

My partner also has BPH symptoms. What should I know?

You may be wondering why your partner has to urinate frequently or urgently many times a day. Or why, even after going to the bathroom, he needs to go again soon. These frustrating BPH Enlargement of the prostate gland that can lead to urination and bladder problems if the enlarged gland begins to press on the urethra. symptoms are likely caused by a medical issue.


Learn everything you can about BPH and available treatment options, and share that information with your partner Once you both have all the facts, your partner can work with his doctor to make a better informed decision about what to do next Talk with your partner about what’s going on and encourage him to visit his doctor to see if he has BPH symptoms Offer to make an appointment for him or to go to the doctor with him